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HomePublications
Drug Discovery Today 2020
Publications

Site-specifically deuterated essential lipids as new drugs against neuronal, retinal and vascular degeneration

BioJiva
August 1, 2020
FEBS Journal 2028-08
Publications

Deuterium-reinforced linoleic acid lowers lipid peroxidation

BioJiva
June 22, 2018
JIMD Reports 2020-07
Publications

Treatment of INAD with RT001: a di-deuterated ethyl ester of linoleic acid. Report of two cases

BioJiva
March 27, 2020
Movement Disorders 2018-06
Publications

Randomized, clinical trial of RT001: early signals of efficacy in Friedreich’s ataxia

BioJiva
April 6, 2018
FEBS Journal 2017-12
Publications

Deuterium-reinforced PUFAs improve cognition in a mouse model of sporadic Alzheimer’s disease

BioJiva
October 27, 2017
Neurobiological Aging 2018-07
Publications

D-PUFAs reduce brain lipid peroxidation and hippocampal amyloid beta-peptide levels

BioJiva
March 5, 2018
Trends in Pharmacological Sciences 2020-04
Publications

PUFA deuteration against neurodegeneration

BioJiva
April 1, 2020
Atherosclerosis 2017-09
Publications

Deuterium-reinforced PUFAs protect against atherosclerosis by lowering lipid peroxidation and hypercholesterolemia

BioJiva
September 6, 2017
Toxicology Letters 2025 01
Publications

Isotopic reinforcement of essential PUFAs diminishes nigrostriatal degeneration in a mouse model of Parkinson’s disease

BioJiva
November 30, 2011
Proc Natl Acad Science 2016-08
Publications

Peroxidation of PUFAs by lipoxygenases drives ferroptosis

BioJiva
August 9, 2016

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Other Publications:

Deuterated docosahexaenoic acid protects against oxidative stress and geographic atrophy-like retinal degeneration in a mouse model with iron overload

BioJiva
March 8, 2022

Plasma and RBC cell membrane accretion and PK of RT001

BioJiva
November 30, 2020

Site-specifically deuterated essential lipids as new drugs against neuronal, retinal and vascular degeneration

BioJiva
August 1, 2020

PUFA deuteration against neurodegeneration

BioJiva
April 1, 2020

Treatment of INAD with RT001: a di-deuterated ethyl ester of linoleic acid. Report of two cases

BioJiva
March 27, 2020

Applications of Deuterium in medicinal chemistry

BioJiva
January 14, 2019
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